ABSTRACT
To determine frequency of Non Alcoholic fatty liver disease in patients with Metabolic Syndrome [MetS]. Cross sectional study. Department of medicine, CMH Okara, Jan 2013 to July 2013. We included 491 adult males, diagnosed with metabolic syndrome [MetS], presenting in outpatient department for routine review. MetS was diagnosed as per the International Diabetes Federation [IDF] proposed criteria of 2004. Detailed history and examination of each individual was done and data entered in pre designed performa. Brightness and posterior attenuation on ultrasound abdomen were considered indices for fatty liver disease in presence of elevated ALT, negative hepatitis serology and absence of alcohol intake. All the data was analyzed using SPSS version 16. p value of less than 0.05 was considered statistically significant. Out of 491 participants with MetS, 222 [45.2%] had fatty liver disease. Mean BMI in patients with metabolic syndrome was 26.1 [ +/- .89] and mean BMI in fatty liver patients was 27.3 [ +/- 0.67].Out of total 5 components of Mets, patients with fatty liver disease had 3.24 [ +/- 0.25] components, as compared to 2.1 [ +/- 0.34] in whole of study group. A large number of patients with metabolic syndrome have fatty liver disease. Fatty liver disease is more frequent in patients who are overweight and those having multiple risk factors of metabolic syndrome
ABSTRACT
To determine frequency of malignancy in solitary thyroid nodule. Case-series study. The study was conducted at Department of Surgery, Combined Military Hospital Rawalpindi, from April 2002 till April 2003. Sixty patients with clinical solitary thyroid nodule fulfilled the selection criteria and were included in the study. Thyroid function tests, ultrasonography and thyroid scanning was done. Finally FNAC and histopathology were done in all the operated cases and record was evaluated. Out of 60 cases studied, 8 [13.33%] were found to have malignant lesions. The remaining 52 [86.67%] cases had benign pathology. Male patients with solitary thyroid nodule showed a higher incidence of malignancy 17.65% as compared to females 11.63%, Maximum malignant cases [50%] were found between the ages of 31 to 40 years. Papillary carcinoma was the most common malignancy [50%] found in our study. The incidence of malignancy in solitary thyroid nodule is quite high [13.33%]. So people should be educated to attend thyroid clinics for early diagnosis and adequate treatment